Blar i forfatter "Tadesse, Margey"

Viser treff 1-3 av 3

    • Antimicrobial natural products from Arctic and sub-Arcticmarine invertebrates 

      Tadesse, Margey (Doctoral thesis; Doktorgradsavhandling, 2010-09-17)
      Infectious diseases are a leading cause of death world-wide and there is a growing need for new anti-infective agents to combat multi-resistant strains of bacteria and fungi. Marine natural products are promising sources of novel antimicrobial compounds. In the present thesis, an investigation into the antimicrobial metabolites of Arctic and sub-Arctic marine invertebrate species is presented. ...

    • Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria 

      Tadesse, Margey; Svenson, Johan; Sepcič, Kristina; Trembleau, Laurent; Engqvist, Stig Olov Magnus; Andersen, Jeanette Hammer; Jaspars, Marcel; Stensvåg, Klara; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-02-14)
      Pulmonarins A and B are two new dibrominated marine acetylcholinesterase inhibitors that were isolated and characterized from the sub-Arctic ascidian <i>Synoicum pulmonaria</i> collected off the Norwegian coast. The structures of natural pulmonarins A and B were tentatively elucidated by spectroscopic methods and later verified by comparison with synthetically prepared material. Both pulmonarins A ...

    • Screening for antibacterial and antifungal activities in marine benthic invertebrates from northern Norway 

      Tadesse, Margey; Gulliksen, Bjørn; Strøm, Morten B.; Styrvold, Olaf B.; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2008-06-18)
      Benthic marine invertebrates collected from sub-Arctic regions of northern Norway, were found to be a promising source of novel bioactive compounds against human and fish pathogenic bacteria and fungi. Lyophilized material from seven species of ascidians, six sponges and one soft alcyonid coral were extracted with 60% acidified acetonitrile (ACN). After separation into an ACN-rich phase (ACN extract) ...